World’s 1st Dengue Vaccine Cleared For Use In Mexico

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MEXICO CITY: The world's first dengue vaccine has won regulatory approval in Mexico, raising hopes that it could prevent more than 100 deaths there a year and eventually millions around the world.

Globally, dengue affects about 400 million people every year, according to the World Health Organization.

The Dengvaxia vaccine is being manufactured by French pharmaceutical giant Sanofi. The company has requested regulatory approval in 20 countries across Asia and Latin America, but Mexico was the first to green flag it.

While the price tag has yet to be decided, the vaccine is likely to generate more than $1billion a year in revenue for Sanofi, said Olivier Charmeil, head of the company's vaccines division. "It's the innovation of the decade," he said.

Mexico's National Vaccination Council will meet to decide whether Dengvaxia will be among the vaccines the government distributes without cost, the head of the health regulatory agency, Mikel Arriola, said. Mexican health authorities estimate the vaccine could prevent 8,000 hospitalizations and 104 deaths per year.

Scientists have long been stumped by dengue, which has four separate strains, forcing researchers to find a drug able to fight all of them at once. Clinical tests, carried out on 40,000 people from 15 countries, have found Dengvaxia can immunize two-thirds of people aged nine years and older, rising to 93% for the more severe form of the disease, dengue hemorrhagic fever.



World’s 1st dengue vaccine cleared for use in Mexico - The Times of India
 
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